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Childhood stroke in Sweden I: incidence, symptoms, risk factors and short-term outcome

S Christerson1, B Strömberg

  • 1Centre for Rehabilitation Research and Paediatric Clinic, Örebro University Hospital, Örebro, Sweden. sten.christerson@orebroll.se

Acta Paediatrica (Oslo, Norway : 1992)
|July 1, 2010
PubMed

Insights

Childhood stroke affects 1.8 per 100,000 children annually. Key risk factors include oral contraceptives, smoking, and anemia, with a 4% mortality rate.

Area of Science:

  • Pediatric Neurology
  • Cerebrovascular Diseases
  • Epidemiology

Background:

  • Childhood stroke is a rare but serious condition.
  • Understanding its incidence, risk factors, and outcomes is crucial for early diagnosis and management.

Purpose of the Study:

  • To determine the incidence, symptoms, diagnostic delay, risk factors, and short-term outcomes of childhood stroke.
  • To analyze population-based data from a Swedish healthcare region.

Main Methods:

  • Retrospective review of medical records for children experiencing their first stroke over a 7-year period.
  • Inclusion criteria: arterial ischemic stroke (AIS), cerebral sinus venous stroke, and non-traumatic hemorrhagic stroke (HS) in children aged 28 days to 18 years.
  • Study covered the Uppsala-Örebro Health Care Region, representing one-fifth of the Swedish population.

Main Results:

  • Identified 51 childhood stroke cases (1.8 per 100,000 children annually).
  • Stroke types: 51% AIS, 41% HS, 8% cerebral sinus venous stroke.
  • Identified risk factors: oral contraceptive use, smoking, iron deficiency anemia. 82% had neurological dysfunction at discharge.

Conclusions:

  • Childhood stroke incidence is 1.8 per 100,000 children/year with 4% primary mortality.
  • Combinations of oral contraceptives, smoking, and anemia are significant risk factors.
  • High rate of neurological dysfunction highlights the need for effective interventions.
Abstract

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