Related Experiment Videos

Multidrug resistant Kluyvera ascorbata septicemia in an adult patient: a case report

Shannon Moonah1, Kavita Deonarine, Clyde Freeman

  • 1Department of Medicine, Howard University Hospital, 2041 Georgia Avenue NW, Washington DC, 20060, USA. smoonah@howard.edu.

Abstract

Insights

This case report details a multidrug-resistant Kluyvera ascorbata bloodstream infection in an adult sepsis patient. The patient achieved a favorable outcome after treatment with meropenem, highlighting a significant clinical finding.

Area of Science:

  • Microbiology
  • Infectious Diseases

Background:

  • Kluyvera ascorbata is an emerging pathogen causing diverse infections.
  • This bacterium can transfer CTX-M-type extended-spectrum beta-lactamase (ESBL) genes to other Enterobacteriaceae.

Purpose of the Study:

  • To report the first case of multidrug-resistant Kluyvera ascorbata bloodstream infection in an adult patient with sepsis.

Main Methods:

  • Case presentation of a 64-year-old male with severe sepsis.
  • Isolation of multidrug-resistant Kluyvera ascorbata from blood cultures.
  • Treatment with meropenem.

Main Results:

  • Successful treatment of severe sepsis caused by multidrug-resistant Kluyvera ascorbata.
  • Favorable clinical outcome observed post-meropenem therapy.

Conclusions:

  • This is the first documented case of multidrug-resistant Kluyvera ascorbata sepsis in an adult.
  • Highlights the clinical significance of Kluyvera ascorbata as a cause of severe infections.

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs like...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...