Related Experiment Video
Updated: Jun 11, 2026

Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
Occupational exposures and obstructive lung disease: a case-control study in hairdressers
Nastran Hashemi1, Mohammad Hossein Boskabady, Ashraf Nazari
1Department of Physiology, Mashhad University of Medical Sciences, Mashhad, Iran, 177948564.
Background:
Hairdressers are exposed to various irritating chemicals during work.
Objective:
This study was designed as a case-control study to evaluate the risk of developing obstructive lung disease in relation to occupational exposures in hairdressers.
Methods:
We interviewed a cohort of 50 female hairdressers and 50 matched controls recruited from a random sample of the general population, using a validated questionnaire for occupational respiratory disease, to compare the prevalence of work-initiated and work-related respiratory symptoms in both groups. We also performed pulmonary function tests (PFTs) in all participants.
Results:
Almost half of the hairdressers reported work-initiated respiratory symptoms. Cough (33%) and breathlessness (29%) were the most common self-reported symptoms after chemical exposures. All respiratory symptoms (cough, breathless, wheezing, and phlegm) were significantly higher in the hairdressers than in the control group (P < .001). The hairdressers reported that bleaching powder and hair spray were the most irritant chemicals that provoke their respiratory symptoms. The impaired PFT values (forced vital capacity, FEV(1), maximum mid-expiratory flow, peak expiratory flow) in the hairdressers, compared to the matched controls, were in line with the questionnaire data.
Conclusions:
Hairdressing work is associated with a high frequency of work-initiated respiratory symptoms and, to a lesser extent, with allergic symptoms, particularly after exposure to bleaching powder and hair spray. PFT values were significantly lower among the hairdressers, which might be a predictor for developing obstructive lung disease.
Related Concept Videos
Chronic Obstructive Pulmonary Disease I: Introduction
Chronic Obstructive Pulmonary Disease-I: Introduction
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One example of...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
PPE Use in Healthcare Settings II: Doffing
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

