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Updated: Jun 11, 2026

Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics (MSPP)
09:43

Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics (MSPP)

Published on: October 30, 2016

Putative household outbreaks of campylobacteriosis typically comprise single MLST genotypes

O Rotariu1, A Smith-Palmer, J Cowden

  • 1Institute of Biological and Environmental Sciences, School of Biological Sciences, University of Aberdeen, Aberdeen, UK.

Epidemiology and Infection
|July 1, 2010
PubMed

Insights

Human Campylobacter infections in Scotland frequently originated from household outbreaks. Multilocus Sequence Typing (MLST) confirmed outbreak strains, highlighting its value in public health for tracking bacterial transmission.

Area of Science:

  • Epidemiology
  • Microbiology
  • Public Health

Background:

  • Campylobacter infections represent a significant public health concern.
  • Household transmission is a recognized, yet often underestimated, route for infectious disease spread.

Purpose of the Study:

  • To investigate the role of household outbreaks in human Campylobacter infections in Scotland.
  • To assess the utility of Multilocus Sequence Typing (MLST) in characterizing strains from household outbreaks.

Main Methods:

  • Analysis of human Campylobacter cases over a 15-month period in Scotland.
  • Identification and investigation of putative household outbreaks.
  • Strain typing using MLST for outbreaks with known composition.

Main Results:

  • 91 household outbreaks accounted for 3.2% of human Campylobacter cases.
  • Of 26 outbreaks with known strain composition, 89% shared the same MLST profile.
  • Household outbreaks involved a larger number of cases compared to general outbreaks.

Conclusions:

  • Household outbreaks are an important source of human Campylobacter infections.
  • MLST is a valuable tool for public health epidemiology in identifying outbreak-related strains.
  • While secondary transmission within households occurs, it appears to be relatively rare.

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