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Postexposure treatment of Marburg virus infection
Thomas W Geisbert1, Lisa E Hensley, Joan B Geisbert
1National Emerging Infectious Diseases Laboratories Institute, Boston, Massachusetts 02118, USA. geisbert@bu.edu
Emerging Infectious Diseases
|July 1, 2010
Abstract:
Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus-based vaccine is administered 20-30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection.
