Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 11, 2026

A Multi-detection Assay for Malaria Transmitting Mosquitoes
09:00

A Multi-detection Assay for Malaria Transmitting Mosquitoes

Published on: February 28, 2015

Detection of Lassa virus, Mali.

David Safronetz1, Job E Lopez, Nafomon Sogoba

  • 1National Institutes of Health, Hamilton, Montana 59840, USA.

Emerging Infectious Diseases
|July 1, 2010
PubMed
Summary

Lassa virus is circulating in southern Mali, a region previously unknown for Lassa fever. Researchers isolated and genetically characterized the virus from small mammals, confirming its presence in the area.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Waning humoral immunity following monkeypox virus infection and vaccination, Canada, 2020 to 2023.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2026
Same author

Searching for immune correlates in Lassa vaccine development - workshop report.

NPJ vaccines·2026
Same author

Pathogenicity and antiviral treatment of clade Ib Monkeypox virus infection in mice.

Antiviral research·2026
Same author

Assessment of three antiviral compounds against Borealpox virus infection in a mouse model.

Emerging microbes & infections·2026
Same author

Inhibitory effects of molnupiravir on Crimean-Congo hemorrhagic fever virus polymerase.

NAR molecular medicine·2026
Same author

Age- and sex-associated differences in Lujo hemorrhagic fever pathogenesis in strain 13/N guinea pigs.

PLoS neglected tropical diseases·2025

Area of Science:

  • Virology
  • Epidemiology
  • Zoonotic Diseases

Background:

  • Lassa fever is a severe zoonotic disease endemic to West Africa.
  • Previous Lassa fever cases in Mali were suspected but not confirmed through viral isolation.
  • A potential Lassa virus infection in a British citizen in Soromba, Mali, in 2009 prompted further investigation.

Purpose of the Study:

  • To investigate the circulation of Lassa virus in small mammal populations in southern Mali.
  • To genetically characterize any isolated Lassa virus strains.
  • To determine if the Soromba area is a potential focus for Lassa virus transmission.

Main Methods:

  • Sampling of small mammals from three villages in southern Mali, including Soromba.
  • Isolation of virus from collected samples.

More Related Videos

A Multiplex Serological Assay for the Detection of Antibody Responses to Arboviruses
05:22

A Multiplex Serological Assay for the Detection of Antibody Responses to Arboviruses

Published on: November 4, 2025

Two-layered Membrane Sandwich Method for Laodelphax striatellus Saliva Collection
06:13

Two-layered Membrane Sandwich Method for Laodelphax striatellus Saliva Collection

Published on: August 27, 2021

Related Experiment Videos

Last Updated: Jun 11, 2026

A Multi-detection Assay for Malaria Transmitting Mosquitoes
09:00

A Multi-detection Assay for Malaria Transmitting Mosquitoes

Published on: February 28, 2015

A Multiplex Serological Assay for the Detection of Antibody Responses to Arboviruses
05:22

A Multiplex Serological Assay for the Detection of Antibody Responses to Arboviruses

Published on: November 4, 2025

Two-layered Membrane Sandwich Method for Laodelphax striatellus Saliva Collection
06:13

Two-layered Membrane Sandwich Method for Laodelphax striatellus Saliva Collection

Published on: August 27, 2021

  • Genetic sequencing and characterization of the isolated Lassa virus.

    • Main Results:

    • Lassa virus was successfully isolated from small mammals in southern Mali.
    • Genetic analysis confirmed the presence of Lassa virus in a previously unrecognized area.
    • The findings indicate active circulation of Lassa virus in the studied region.

    Conclusions:

    • Lassa virus is actively circulating in southern Mali, extending the known endemic region.
    • This discovery highlights the need for enhanced surveillance and public health measures in the area.
    • Further research is warranted to understand the ecology and transmission dynamics of Lassa virus in this region.