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Perimenopausal postpartum depression after conception by assisted reproductive technology
Michael D McIntosh1, Stephen Ferrando
1Weill Medical College of Cornell University, 21 Bloomingdale Road, White Plains, NY 10605, USA. mdm2006@med.cornell.edu
Background:
Women conceiving after the onset of the menopausal transition may experience hormonal fluctuations that predispose them to postpartum depression. Conception by assisted reproductive technology (ART) may increase this risk.
Objective:
This case report highlights the hormonal and pathophysiological changes that may contribute to the development of postpartum depression during perimenopause.
Method:
The authors report on the case of a perimenopausal woman who developed postpartum depression after conception by ART.
Results:
The patient responded well to antidepressant treatment, estrogen replacement, and psychotherapy.
Conclusion:
Research into perimenopausal postpartum depression in the setting of ART may lead to improved screening and treatment for at-risk patients.
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