[Evaluation of ovarian response in ovulation induction]

To decrease the cost of determining estrogens by the High Estrotex (Mochida Pharmaceutica, Japan) method, the authors have modified it, thus reducing the usage of expensive reagents four times. The modified method was applied to evaluate estrogens in 27 infertile patients when stimulating superovulation. The findings were in agreement with the results obtained by foreign special clinics engaged in treating infertility with extracorporeal fertilization followed by embryonal transfer. The pregnancy rate in the females was 15% on an embryonal transfer basis. The modified High-Estrotex method is easy-to-use, rapid, and cost-effective in the measurement of daily urinary estrogen levels. It may be employed both in extracorporeal fertilization and embryonal transfer and in cases which require daily multiple and reliable evaluation of an ovarian response to ovulation inducers.