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Amyloidosis secondary to xanthogranulomatous pyelonephritis: a rare association
Rajpal Singh Punia1, Neerja Dhingra, Harsh Mohan
1Department of Pathology, Government Medical College and Hospital, Chandigarh, India.
Abstract:
Xanthogranulomatous pyelonephritis and secondary systemic amyloidosis are relatively common pathologies with innumerable cases being reported now and then. However the association of these entities is an extremely uncommon occurrence with only ten cases described in the literature. Clinical remission of amyloidosis develops in a majority of these patients after removal of the renal lesion. We present a case of this rare association in a young female who under-went nephrectomy for a non-functioning kidney. A histopathological diagnosis of xanthogranulomatous pyelonephritis was made. In addition there were deposits of amyloid in the glomeruli and the interstitial blood vessels.
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