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Pediatric urolithiasis in the central coast of Tunisia: Epidemiologic changes over the past twenty-five years
1Department of Biochemistry and Toxicology, Fattouma Bourguiba Hospital, Monastir, Tunisia. akram_alaya@yahoo.co.uk
Insights
Pediatric urolithiasis incidence is declining, with a rise in calcium oxalate stones and a decrease in infection-related stones in children over 25 years.
Area of Science:
- Urology
- Pediatric Nephrology
- Epidemiology
Background:
- Pediatric urolithiasis incidence has shown a declining trend in Tunisia and other Mediterranean regions over the past 25 years.
- Understanding the changing composition of pediatric kidney stones is crucial for effective management.
Purpose of the Study:
- To analyze the incidence and composition of urolithiasis in pediatric patients.
- To identify trends in stone types over a 25-year period.
Main Methods:
- Retrospective analysis of pediatric urolithiasis cases.
- Evaluation of stone composition over the study period (1982-2007).
Main Results:
- A consistent decrease in the overall incidence of pediatric urolithiasis was observed.
- The prevalence of calcium oxalate stones increased, while infection-related stones (struvite) decreased.
- Whewellite, a form of calcium oxalate, was more common in school-aged children.
Conclusions:
- Improved diagnostics and treatment of urinary tract infections in children likely contributed to the decrease in struvite stones.
- The shift towards calcium oxalate stones highlights evolving etiological factors in pediatric urolithiasis.
Abstract:
The incidence of pediatric urolithiasis has been constantly decreasing during the past twenty-four years (1982-2007) in Tunisia as well as in other Mediterranean countries. This study was undertaken to observe the incidence of stone disease and its composition in children. Our study shows a downward trend of incidence of urolithiasis in pediatric patients over the last 25 years. The prevalence of calcium oxalate stones has constantly increased with decrease in the stones related to infections Whewellite (calcium oxalate) was more frequent in children of school age. In conclusion, the decrease in struvite frequency in children patients during the past twenty-five years and the stabilization of calcium phosphate stones are the result of a significant improvement of diagnostics and the treatment of urinary tract infections in the young children in our country.
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