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Mucoepidermoid carcinoma: a retrospective study
S A Miguens1, A C Uchoa Vasconcelos, M A Figueiredo
1School of Dentistry, Luteran University of Brazil, Canoas, Rio Grande do Sul, Brazil.
Minerva Stomatologica
|July 1, 2010
Summary
Mucoepidermoid carcinoma, a rare oral cancer, predominantly affects middle-aged males and commonly occurs in minor salivary glands, particularly the palate. Symptoms like pain and irritation are frequent, regardless of tumor grade.
Area of Science:
- Oral pathology
- Oncology
- Histopathology
Background:
- Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy.
- Understanding its demographic and clinical characteristics is crucial for diagnosis and management.
Purpose of the Study:
- To review cases of mucoepidermoid carcinoma diagnosed at São Lucas Hospital (PUCRS).
- To analyze patient demographics, clinical presentation, and histological features of MEC.
Main Methods:
- Retrospective review of medical charts from 1978-2009.
- Data collected included patient sex, age, clinical appearance, anatomical site, symptoms, lesion size, and histological grade.
Main Results:
- 12 cases of MEC identified among 19,383 patients (0.06%).
- Mean patient age was 43.8 years, with a male predilection (58.7%).
- Palate (41.7%) was the most common site in minor salivary glands; 50% reported pain/irritation.
Conclusions:
- MEC is a rare malignancy in the oral and maxillofacial region.
- Clinical presentation and histological grade showed no clear correlation with symptoms.
