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Related Experiment Video

Updated: Jun 11, 2026

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

Published on: March 22, 2012

Temporal-imaging system with simple external-clock triggering.

Daniel H Broaddus¹, Mark A Foster, Onur Kuzucu

¹School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA. dhb29@cornell.edu

|July 1, 2010

Summary

This summary is machine-generated.

This study introduces a novel temporal imaging system using parametric mixing and a time-lens-based pump laser for precise waveform characterization. The system achieves high resolution and extended record lengths, enabling advanced temporal measurements.

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Area of Science:

Optics and Photonics
Ultrafast Science
Metrology

Background:

Accurate characterization of ultrafast temporal waveforms is crucial for advancements in various scientific fields.
Existing temporal measurement techniques often face limitations in resolution, record length, or operational complexity.

Purpose of the Study:

To develop and demonstrate a versatile temporal imaging system.
To enable high-resolution characterization of temporal waveforms.
To showcase the system's integration into different measurement schemes.

Main Methods:

Utilized parametric mixing for temporal imaging.
Employed a time-lens-based pump laser for external clock triggering.
Integrated the system into time-to-frequency and temporal magnification schemes.

Main Results:

Achieved 1.4-ps resolution and a 530-ps record length in time-to-frequency measurements.
Demonstrated single-shot temporal magnification with a 113x factor, 1.5-ps resolution, and 220-ps record length.

Conclusions:

The developed temporal imaging system offers a robust and flexible platform for ultrafast waveform analysis.
The system's ability to perform high-resolution measurements in different configurations highlights its potential for diverse scientific applications.