Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safety and functional evaluation of a synthetic lamina cover that replaces lost autologous spinal bone after laminectomy, in a sheep and human study.

North American Spine Society journal·2025
Same author

The best pooling strategy to reduce polymerase chain reaction tests during the coronavirus disease-19 pandemic at low prevalence.

Tzu chi medical journal·2025
Same author

All-van-der-Waals Heterostructure of MoS<sub>2</sub> Grating and InSe Flake for Spectrally Selective Polarization-Sensitive Photodetection in NIR Region.

ACS nano·2025
Same author

Manipulation on radiation angles via spatially organized multipoles with vertical split-ring resonators.

Nanophotonics (Berlin, Germany)·2024
Same author

Surface-wave coupling in double Floquet sheets supporting phased temporal Wood anomalies.

Nanophotonics (Berlin, Germany)·2024
Same author

Morbid obesity is associated with outcomes in patients undergoing vertebroplasty or kyphoplasty for osteoporotic vertebral compression fractures: a nationwide inpatient sample analysis.

Journal of neurointerventional surgery·2024

Related Experiment Video

Updated: Jun 11, 2026

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets
06:12

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

Published on: March 17, 2023

A multi-functional plasmonic biosensor.

Yun-Tzu Chang1, Yueh-Chun Lai, Chung-Tien Li

  • 1Department of Materials Science and Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan, Republic of China.

Optics Express
|July 1, 2010
PubMed
Summary

We developed a new refractive index sensor using nanostructured split ring resonators (SRRs). This multi-mode sensor offers tunable sensitivity for detecting various biological events without labels.

More Related Videos

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions
09:09

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions

Published on: November 23, 2015

Related Experiment Videos

Last Updated: Jun 11, 2026

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets
06:12

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

Published on: March 17, 2023

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions
09:09

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions

Published on: November 23, 2015

Area of Science:

  • Plasmonics
  • Nanotechnology
  • Biosensing

Background:

  • Refractive index sensing is crucial for detecting biological analytes.
  • Existing sensors often require complex coupling mechanisms.
  • Nanostructured materials offer unique optical properties for sensing applications.

Purpose of the Study:

  • To present a coupler-free, multi-mode refractive index sensor based on nanostructured split ring resonators (SRRs).
  • To establish a design rule for multi-mode refractive-index (MMRI) sensors using a standing-wave plasmonic resonance model.
  • To demonstrate the sensor's capability for detecting events at different length scales.

Main Methods:

  • Fabrication of nanostructured split ring resonators (SRRs).
  • Characterization of reflectance peaks and their sensitivity to the dielectric environment.
  • Application of a standing-wave plasmonic resonance model for quantitative description.
  • Investigation of mode-dependent sensitivity and detection lengths.

Main Results:

  • SRR structures exhibited multiple, sensitive reflectance peaks.
  • A quantitative model was developed for MMRI sensor design.
  • Lower-order modes showed high sensitivity with short detection lengths (<500 nm).
  • Higher-order modes offered mediate sensitivity with longer detection lengths (microns) for intracellular detection.

Conclusions:

  • The SRR-based sensor is a multi-functional, coupler-free biosensor.
  • It enables label-free detection with tunable sensitivity.
  • The sensor holds potential as a label-free imaging device for biological applications.