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Related Concept Videos

X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.

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Related Experiment Video

Updated: Jun 11, 2026

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating
10:39

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Published on: October 11, 2016

Large phase-stepping approach for high-resolution hard X-ray grating-based multiple-information imaging.

Zhifeng Huang1, Zhiqiang Chen, Li Zhang

  • 1Department of Engineering Physics, Tsinghua University, Beijing 100084, China. huangzhifeng@mail.tsinghua.edu.cn

Optics Express
|July 1, 2010
PubMed
Summary

A new large phase-stepping approach for hard X-ray grating imaging simplifies equipment needs. This advancement in grating-based multiple-information imaging technology lowers resolution requirements for wider commercial use.

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Last Updated: Jun 11, 2026

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating
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Area of Science:

  • Medical imaging
  • Industrial applications
  • X-ray physics

Background:

  • High-resolution hard X-ray grating-based imaging offers simultaneous attenuation, refraction, and scattering data.
  • This technology is considered a next-generation imaging method for medical and industrial fields.

Purpose of the Study:

  • To present a large phase-stepping approach that reduces the need for high positioning resolution.
  • To demonstrate the feasibility of this new approach through theoretical deduction and experimental validation.

Main Methods:

  • A large phase-stepping technique with significantly lower movement resolution was developed.
  • The approach was theoretically analyzed and experimentally verified using a grating-based imaging setup.

Main Results:

  • The new method effectively substitutes the conventional high-positioning-resolution phase-stepping approach.
  • Experiments confirmed the viability of the lower-resolution technique.

Conclusions:

  • The developed large phase-stepping approach relaxes stringent positioning resolution and environmental requirements.
  • This innovation facilitates the future commercialization of grating-based multiple-information imaging technology.