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Related Experiment Videos

The pleural tail sign.

W R Webb

    Radiology
    |May 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    The pleural tail sign, often linked to cancer, can also appear in benign conditions. Nodules 2 cm or larger with this sign suggest malignancy, while smaller ones are typically benign.

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    Area of Science:

    • Radiology
    • Oncology
    • Pathology

    Background:

    • The pleural tail sign is a radiographic finding often associated with malignancy.
    • Its diagnostic accuracy in differentiating benign from malignant lesions requires further investigation.

    Purpose of the Study:

    • To evaluate the association between the pleural tail sign and malignancy.
    • To determine if nodule size can reliably differentiate benign from malignant lesions presenting with a pleural tail sign.

    Main Methods:

    • Retrospective review of 18 patients with the pleural tail sign.
    • Analysis of tumor types, nodule characteristics, and histological findings.
    • Correlation of nodule size with benign or malignant diagnosis.

    Main Results:

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    • Nine out of 18 patients (50%) with the pleural tail sign had benign disease.
    • Malignant diagnoses included bronchioloalveolar carcinoma, adenocarcinoma, squamous-cell carcinoma, and metastatic colon adenocarcinoma.
    • Nodules ≥2 cm were malignant, whereas nodules ≤1 cm were benign.
    • Radiographic characteristics of the pleural tails and nodule location did not differentiate benign from malignant lesions.

    Conclusions:

    • The pleural tail sign is not exclusively indicative of malignancy and can be associated with benign conditions.
    • Nodule size is a significant factor in distinguishing benign from malignant lesions with a pleural tail sign.
    • Histologically, pleural tails represent fibrotic changes, often associated with desmoplastic reactions in neoplasms.