Juvenile nasopharyngeal angiofibroma. A report of seven cases

Seven cases of biopsy-proved juvenile nasopharyngeal angiofibroma are presented. All patients were males. Examination under anesthesia and tomography and angiography were very rewarding in determining the full extent of tumor. Selective carotid angiography revealed a characteristic early arterial phase with reticulated vessels, and a homogeneous blush continuing into the venous phase without early draining veins. The tumor has a strong predilection for young males. Chromosomal studies and estimation of 17-ketosteroids in 4 patients were normal. None of the patients demonstrated sexual underdevelopment. All were treated by external radiotherapy with 3000 rads in 15 fractions in three weeks with good results. There were no undue side effects.