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Updated: Jun 11, 2026

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Published on: May 22, 2026
Effects of complementary therapy on health in a national U.S. sample of older adults
Ha T Nguyen1, Joseph G Grzywacz, Wei Lang
1Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. hnguyen@wfubmc.edu
Objectives:
The study objectives were to identify types of complementary therapy that are most predictive of health outcomes, including functional status, physical health-related quality of life (HRQoL), and mental HRQoL among older adults.
Design:
This was a prospective study.
Settings/Location:
The study comprised computer-assisted interviews conducted in participants' homes.
Subjects:
Subjects included 1683 adults aged 55 and older who participated in the 2002 National Health Interview Survey and the 2003 Medical Expenditure Panel Survey.
Intervention:
None.
Outcome Measures:
Functional status, physical HRQoL, and mental HRQoL at 1-year follow-up.
Results:
The use of biologically based therapies predicted better functional status, such that users reported less functional impairment than nonusers (p < 0.01), adjusting for age, gender, race/ethnicity, education, health insurance, household income, and comorbid conditions. Users of manipulative and body-based methods reported less functional impairment (p < 0.05). They also reported better physical and mental health-related quality of life, though these relationships were marginally significant. Other groups of therapies, alternative medical systems, mind-body therapies, and prayer were not predictive of either functional status or HRQoL.
Conclusions:
Favorable effects were observed among users of biologically based therapies and users of manipulative and body-based methods. Other types of complementary therapy had no effects on health status over a 1-year follow-up period.
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