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Ascending placentitis in the mare: an update.

M M LeBlanc1

  • 1Rood and Riddle Equine Hospital, Lexington, KY 40580, USA. mleblanc@roodandriddle.com

Reproduction in Domestic Animals = Zuchthygiene
|July 2, 2010
PubMed
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Ascending placentitis can cause foal loss. Early diagnosis using ultrasonography and hormone levels, combined with prompt antibiotic treatment, improves foal survival rates in experimental models.

Area of Science:

  • Veterinary Medicine
  • Reproductive Biology

Background:

  • Ascending placentitis frequently leads to premature birth, abortion, and compromised foals.
  • Experimental models are crucial for developing diagnostic and therapeutic strategies to enhance live foal rates.

Purpose of the Study:

  • To investigate diagnostic procedures and treatment strategies for ascending placentitis.
  • To improve the outcomes of pregnancies affected by placentitis.

Main Methods:

  • Utilizing transrectal and transabdominal ultrasonography for fetal well-being and placental assessment.
  • Measuring plasma progestins and estrogens to detect fetal stress or hypoxia.
  • Implementing treatments including antibiotics, tocolytics, and immunomodulators to combat infection and inflammation.

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Main Results:

  • Early intervention is critical for saving pregnancies affected by placentitis.
  • Prompt, aggressive antibiotic treatment has demonstrated improved foal viability in experimental settings.

Conclusions:

  • Effective management of ascending placentitis requires early diagnosis and prompt, multi-modal treatment.
  • Antibiotics play a key role in improving foal viability in placentitis models.