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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Why statin therapy may increase the risk for posttransplantation squamous cell carcinoma
Luca Mascitelli1, Francesca Pezzetta, Mark R Goldstein
1Comando Brigata Alpina Julia, Medical Service, 8 Via S. Agostino, Udine, 33100, Italy. lumasci@libero.it
Abstract:
We suggest that surveillance for squamous cell cancer might be particularly useful for transplant patients receiving statin therapy. We recommend that development of non melanoma skin cancer should be specified as a secondary endpoint in future large endpoint statin trials, and suggest that in transplant patients the adverse effects of statin drugs may outweigh benefits, especially in women and the elderly, a subset of population in which even individuals at high risk for cardiovascular disease have shown no trend to net benefit from statins.
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