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Updated: Jun 11, 2026
09:43
Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
[Biomarkers in lupus nephritis]
Boglárka Brúgós1, Margit Zeher
1Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Belgyógyászati Intézet, III. Belgyógyászati Klinika, Klinikai Immunológiai Tanszék, Debrecen Nagyerdei krt. 98. 4032. brugosb@gmail.com
Orvosi Hetilap
|July 2, 2010
Summary
Identifying reliable biomarkers is crucial for managing systemic lupus erythematosus (SLE) and lupus nephritis flares. This review covers established and novel biomarkers for monitoring disease activity and treatment effectiveness.
Area of Science:
- Immunology
- Nephrology
- Rheumatology
Context:
- Systemic lupus erythematosus (SLE) is a complex autoimmune disease affecting multiple organs.
- Lupus nephritis, a severe complication of SLE, requires vigilant monitoring.
- Early detection of complications and flares is essential for effective management.
Purpose:
- To review current and emerging biomarkers for monitoring SLE and lupus nephritis flares.
- To highlight the need for improved diagnostic and prognostic tools.
- To discuss biomarkers beyond routine serological tests.
Summary:
- This review examines conventional serological tests and novel, experimental biomarkers for SLE flare activity.
- It specifically details biomarkers relevant to lupus nephritis.
- The focus is on identifying markers for early detection, prediction, and treatment follow-up.
Impact:
- Aims to guide clinicians in selecting appropriate biomarkers for lupus nephritis management.
- Facilitates earlier intervention and personalized treatment strategies.
- Contributes to improved patient outcomes in SLE and lupus nephritis.
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