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Updated: Jun 11, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Do all ischemic stroke subtypes benefit from organized inpatient stroke care?
E E Smith1, K A Hassan, J Fang
1Calgary Stroke Program, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada T2N 2T9. eesmith@ucalgary.ca
Organized stroke care, measured by the organized care index (OCI), significantly reduces 30-day mortality across all ischemic stroke subtypes. These findings support universal implementation of structured stroke care protocols.
Area of Science:
- Neurology
- Public Health
- Healthcare Management
Background:
- Limited real-world data exist on organized stroke care effectiveness across ischemic stroke subtypes.
- This study investigates the impact of structured stroke care on mortality in diverse stroke populations.
Purpose of the Study:
- To analyze the association between organized stroke care and 30-day mortality in patients with different ischemic stroke subtypes.
- To determine if the benefits of organized stroke care vary by stroke classification.
Main Methods:
- A longitudinal cohort study of 6,223 ischemic stroke patients (July 2003-September 2007) from the Canadian Stroke Network Registry.
- Ischemic stroke subtypes classified using Trial of Org 10172 in Acute Stroke Treatment criteria: large artery atherosclerotic disease, lacunar, cardioembolic, and other.
- Organized stroke care quantified using the organized care index (OCI), assessing occupational therapy, physiotherapy, stroke team assessment, and stroke unit admission.
Main Results:
- Higher OCI scores (2-3 vs. 0-1) were strongly linked to reduced 30-day mortality across all ischemic stroke subtypes (adjusted ORs 0.16-0.43, p < 0.001).
- The association between higher OCI and lower mortality persisted after excluding palliative care patients.
- Numbers needed to treat to prevent one 30-day death ranged from 4 to 9, indicating significant treatment benefit.
Conclusions:
- A robust association exists between higher levels of organized stroke care (OCI) and decreased 30-day mortality, irrespective of ischemic stroke subtype.
- These findings advocate for the universal provision of organized stroke care to all stroke patients to improve survival outcomes.
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