Carcinoid crisis 24 hours after bland embolization: A case report
1Department of Molecular Pharmacology, City of Hope National Medical Center, Duarte, CA, USA.
Bioscience Trends
|July 2, 2010
Summary
Bland embolization of carcinoid liver metastasis can trigger a carcinoid crisis. Octreotide administration before and after the procedure is crucial for preventing and treating this critical event.
Area of Science:
- Interventional Radiology
- Oncology
- Endocrinology
Background:
- Carcinoid liver metastasis can lead to severe complications.
- Bland embolization is a treatment option for liver metastases.
- Carcinoid crisis is a life-threatening condition associated with neuroendocrine tumors.
Observation:
- A patient undergoing bland embolization for carcinoid liver metastasis developed symptoms within 24 hours.
- The patient experienced flushing and severe hypotension.
- These symptoms were consistent with a carcinoid crisis.
Findings:
- Bland embolization of carcinoid liver metastasis can precipitate carcinoid crisis.
- Octreotide is effective in managing carcinoid crisis.
Implications:
- Prophylactic octreotide administration is recommended before and after bland embolization.
- This approach is vital for preventing and treating carcinoid crisis in patients with carcinoid liver metastasis.
- Highlights the importance of multidisciplinary management for neuroendocrine tumor treatment.
