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Updated: Jun 11, 2026

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Multifocal Electroretinograms
Published on: December 4, 2011
Structural-functional dissociation in presumed ethambutol optic neuropathy.
Daniel Masvidal1, Richard K Parrish, Byron L Lam
1Bascom Palmer Eye Institute, School of Medicine and Miami Children's Hospital, University of Miami Miller, Miami, Florida 33136, USA.
Summary
Ethambutol (EMB) optic neuropathy can cause vision loss, but visual function may improve even with ongoing optic nerve damage. This case highlights the disconnect between structural changes and functional recovery in EMB optic neuropathy.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Neurology
Background:
- Pulmonary Mycobacterium avium intracellulare infections often require multi-drug therapy.
- Ethambutol is a key component in treating Mycobacterium avium intracellulare infections.
- Ethambutol optic neuropathy is a known, potentially vision-threatening side effect.

