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Updated: Jun 11, 2026
08:50
Direct Observation of Phagocytosis and NET-formation by Neutrophils in Infected Lungs using 2-photon Microscopy
Published on: June 2, 2011
[Laryngeal and pharyngeal actinomycosis]
R Schumann1, K J Lorenz, M Tisch
1Klinik für HNO-Heilkunde/Kopf- und Halschirurgie, Bundeswehrkrankenhaus Ulm, Oberer Eselsberg 40, 89081, Ulm, Deutschland.
HNO
|July 2, 2010
Summary
Cervicofacial actinomycosis, a rare infection mimicking cancer, can occur in the throat after trauma. This case highlights the diagnostic challenge of distinguishing this condition from malignancy.
Area of Science:
- Infectious Diseases
- Otolaryngology
- Pathology
Background:
- Cervicofacial actinomycosis is an uncommon bacterial infection, typically originating from dental issues.
- Pharyngeal and laryngeal involvement is rare, often secondary to mucosal trauma, and can resemble malignancy.
Observation:
- A 56-year-old male presented with a large, necrotic oropharyngeal, hypopharyngeal, and laryngeal mass.
- The lesion, initially suspected as a tumor, was diagnosed as cervicofacial actinomycosis six months after ingesting an ear of corn.
Findings:
- The case underscores the diagnostic difficulty in differentiating rare actinomycosis presentations from upper aerodigestive tract cancers.
- Histopathological examination confirmed cervicofacial actinomycosis despite its unusual location and presentation.
Implications:
- This case emphasizes the importance of considering actinomycosis in the differential diagnosis of neck masses, especially with a history suggestive of mucosal trauma.
- Accurate diagnosis and timely treatment are crucial for managing cervicofacial actinomycosis and avoiding misdiagnosis as cancer.
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