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Imaging and Analysis of Neurofilament Transport in Excised Mouse Tibial Nerve
09:52

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Published on: August 31, 2020

Diffusion tensor imaging of peripheral nerves.

Sachin Jambawalikar1, Jeremy Baum, Terry Button

  • 1SUNY Stony Brook University Medical Center, Stony Brook, NY, USA.

Skeletal Radiology
|July 2, 2010
PubMed
Summary
This summary is machine-generated.

Diffusion tensor imaging (DTI) visualizes the ulnar nerve, measuring water diffusion. This study found fractional anisotropy (FA) of 0.752 and apparent diffusion coefficient (ADC) of 0.96 × 10⁻³ mm²/s in healthy volunteers.

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Area of Science:

  • Neuroimaging
  • Biomedical Engineering
  • Physics

Background:

  • Magnetic resonance diffusion tensor imaging (DTI) is a powerful technique for studying water diffusion in biological tissues.
  • DTI analysis provides quantitative metrics like fractional anisotropy (FA) and apparent diffusion coefficient (ADC), and enables three-dimensional fiber tractography.

Purpose of the Study:

  • To visualize the ulnar nerve using DTI in healthy volunteers.
  • To provide a detailed explanation of the physical principles underlying DTI for educational purposes.

Main Methods:

  • Diffusion tensor imaging (DTI) was performed on ten healthy volunteers.
  • Image data analysis included calculation of FA, ADC, and 3D tractography of the ulnar nerve.

Main Results:

  • Fractional anisotropy (FA) of the ulnar nerve was determined to be 0.752 ± 0.067.
  • Apparent diffusion coefficient (ADC) was measured as 0.96 ± 0.13 × 10⁻³ mm²/s.

Conclusions:

  • DTI successfully visualized the ulnar nerve in healthy individuals.
  • The study provides normative FA and ADC values for the ulnar nerve, contributing to the understanding of peripheral nerve imaging.