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Related Experiment Video

Updated: Jun 11, 2026

Single-port Non-liposuction Endoscopic Axillary Lymph Node Dissection in Breast Cancer Surgery
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Sentinel lymph node biopsy in patients with previous ipsilateral complete axillary lymph node dissection.

Paramjeet Kaur1, John V Kiluk, Tammi Meade

  • 1H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.

Annals of Surgical Oncology
|July 2, 2010
PubMed
Summary

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Reoperative sentinel lymph node (SLN) biopsy is feasible after prior axillary lymph node dissection for breast cancer recurrence. This procedure can identify alternative lymphatic drainage and impact disease staging and local control.

Area of Science:

  • Oncology
  • Surgical Oncology
  • Breast Cancer Research

Background:

  • Prior ipsilateral completion axillary lymph node dissection (CALND) may contraindicate sentinel lymph node (SLN) mapping for recurrent breast carcinoma.
  • Reoperative SLN biopsy can identify alternative lymphatic drainage pathways post-axillary dissection.
  • Metastatic disease in reoperative SLN biopsy can affect cancer staging and locoregional control.

Purpose of the Study:

  • To evaluate the feasibility and impact of reoperative SLN biopsy in breast cancer patients with prior CALND.
  • To determine if alternative lymphatic drainage pathways exist after axillary dissection.
  • To assess the role of reoperative SLN biopsy in staging and locoregional control of recurrent breast cancer.

Main Methods:

  • Utilized an institutional breast cancer database and electronic health records (1994-2007).

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  • Queried for patients with prior CALND who underwent reoperative SLN biopsy.
  • Collected demographic, clinical, and treatment variables for analysis.
  • Main Results:

    • Identified 45 patients (0.7%) with prior CALND who underwent reoperative SLN mapping and biopsy.
    • Achieved successful ipsilateral reoperative SLN mapping and biopsy in 13 patients (29%).
    • Identified nonaxillary lymphatic drainage in 5 patients.

    Conclusions:

    • Reoperative SLN mapping and biopsy is a feasible procedure for breast cancer recurrence after prior CALND.
    • This technique provides crucial staging information.
    • Identifies extra-axillary drainage, potentially influencing staging and local disease control.