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Related Concept Videos

Precipitation Gravimetry01:03

Precipitation Gravimetry

Precipitation gravimetry is based on converting an analyte into a sparingly soluble precipitate, which is separated by filtration and weighed. An ideal precipitate should be pure, insoluble, of known composition, and easily filtered from the reaction mixture.
In determining nickel by gravimetric analysis, a precipitant of ethanolic dimethylglyoxime is added to a hot nickel salt solution. This is quickly followed by the dropwise addition of dilute ammonia solution until precipitation occurs. A...
Gravimetry: Overview01:05

Gravimetry: Overview

Gravimetric analysis is a quantitative method where the analyte is isolated and weighed directly or after conversion into a substance of known composition. Gravimetric analysis can be classified as precipitation, electrogravimetry, volatilization, and particulate gravimetry, based on the method used to isolate the analyte.
In precipitation gravimetry, the analyte is converted into a precipitate and weighed. For example, the silver content in a sample can be estimated by precipitating and...

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Updated: Jun 11, 2026

Development of New Methods for Quantifying Fish Density Using Underwater Stereo-video Tools
09:32

Development of New Methods for Quantifying Fish Density Using Underwater Stereo-video Tools

Published on: November 20, 2017

SEDVIEW, real-time sedimentation analysis.

David B Hayes1, Walter F Stafford

  • 1MedImmune, Inc., Analytical Biochemistry, Gaithersburg, MD 20878, USA. HayesD@MedImmune.com

Macromolecular Bioscience
|July 2, 2010
PubMed
Summary
This summary is machine-generated.

This study introduces SEDVIEW, a novel software package enabling real-time analysis of sedimentation coefficient distributions during analytical ultracentrifugation runs. This allows for early assessment of sample quality and heterogeneity, saving significant time.

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Area of Science:

  • Biophysical Chemistry
  • Analytical Chemistry
  • Biochemistry

Background:

  • Existing analytical ultracentrifugation software lacks real-time analysis capabilities.
  • Early assessment of sample quality and heterogeneity is crucial for efficient experimental design.
  • Current methods often require run completion or offline analysis of early scans.

Purpose of the Study:

  • To develop a software package for real-time analysis of sedimentation coefficient distributions.
  • To enable early determination of sample quality and heterogeneity during analytical ultracentrifugation.
  • To reduce the time required for obtaining critical sample information.

Main Methods:

  • Development of a new software package named SEDVIEW.
  • Implementation of real-time data processing for sedimentation coefficient distributions.
  • Integration of early analysis features within the ultracentrifugation workflow.

Main Results:

  • SEDVIEW provides real-time sedimentation coefficient distribution analysis.
  • The software allows for early identification of the number of components in a sample.
  • Early assessment of sample heterogeneity is now feasible during the run.

Conclusions:

  • SEDVIEW facilitates timely evaluation of sample characteristics in analytical ultracentrifugation.
  • The software enhances experimental efficiency by enabling real-time decision-making.
  • SEDVIEW addresses the need for immediate feedback on sample quality and composition.