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Related Concept Videos

Good Manufacturing Practices01:26

Good Manufacturing Practices

Good Manufacturing Practices (GMP) constitute a foundational set of guidelines that ensure the production of safe, consistent, and high-quality products, particularly in industries such as pharmaceuticals, biotechnology, and food processing. These protocols encompass all aspects of production, from the sourcing of raw materials to the final distribution of the finished product.A core pillar of GMP is stringent hygiene and sanitation across all production environments. This includes routine...

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Workplace practices for engineered nanomaterial manufacturers.

Susan Woskie1

  • 1Department of Work Environment, University of Massachusetts Lowell, Lowell, MA 01854, USA. Susan_woskie@uml.edu

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
|July 2, 2010
PubMed
Summary

A precautionary approach is recommended for handling engineered nanomaterials (ENM) due to potential health hazards. Comprehensive workplace safety programs incorporating a hierarchy of controls are essential for managing ENM risks.

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Area of Science:

  • Occupational Health and Safety
  • Nanotechnology
  • Toxicology

Background:

  • The rapid growth of nanotechnology necessitates occupational health and safety (OHS) guidelines for engineered nanomaterials (ENM).
  • Emerging nanotoxicology research indicates potential health risks associated with certain nanoparticles.
  • Comprehensive risk assessments for all ENM types are currently not feasible.

Purpose of the Study:

  • To recommend a precautionary approach for handling ENM in laboratory and manufacturing settings.
  • To advocate for the development of robust OHS programs for workers exposed to ENM.
  • To outline a hierarchy of exposure control methods for managing ENM risks.

Main Methods:

  • Review of existing occupational health and safety principles.
  • Application of the hierarchy of controls (elimination, substitution, engineering controls, administrative controls, personal protective equipment).
  • Consideration of the precautionary principle in the absence of complete risk data.

Main Results:

  • Evidence supports the effectiveness of various exposure control methods for ENM.
  • A multi-faceted approach integrating different controls is achievable.
  • The specific application of controls depends on the ENM and its use.

Conclusions:

  • A precautionary approach is vital for managing ENM due to unknown risks.
  • Comprehensive OHS programs should integrate a hierarchy of controls.
  • Effective exposure control strategies are crucial for worker safety in nanotechnology.