Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cognitive Development During Adulthood

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...

Depression: Overview

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...

Negative and Cognitive Symptoms of Schizophrenia

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...

Depressive Disorders: MDD and Dysthymia

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...

Depressive Disorders: Etiology

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

Erikson's Theory on Socioemotional Development during Adulthood

Erikson's Theory on Socioemotional Development during Adulthood

Erik Erikson's theory of psychosocial development outlines a series of stages through which individuals progress across the lifespan. Each stage involves a psychosocial conflict that significantly influences personal growth and well-being. Three key stages — intimacy versus isolation, generativity versus stagnation, and integrity versus despair — highlight the developmental challenges faced in adulthood.
Intimacy Versus Isolation in Early Adulthood
Individuals in early adulthood, from the 20s...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Three-order interactions in the alpha band of default mode network EEGs based on O-information rate: insights from aging and Alzheimer's disease.

Alzheimer's research & therapy·2026

Same author

Amygdala and hippocampal volumes as neural correlates of resilience and loneliness in older adults.

Neurobiology of aging·2026

Same author

Impact of Transcranial Direct Current Stimulation-Induced Electric Fields on Slowing Cognitive Decline in Older Adults With Mild Cognitive Impairment or Remitted Major Depressive Disorder: An Analysis of the PACt-MD Randomized Clinical Trial.

Biological psychiatry·2026

Same author

Comparison of functional disability in older surgical patients with and without probable cognitive impairment: A longitudinal prospective cohort study.

Journal of anesthesia and translational medicine·2026

Same author

Angiogenesis markers and cognitive response in a randomized trial of cognitive remediation plus transcranial direct current stimulation in older adults at risk of dementia.

Journal of Alzheimer's disease : JAD·2026

Same author

Brain Structures and Cognitive Decline: Moderation Analysis of the PACt-MD Randomized Clinical Trial of Brain Stimulation Plus Cognitive Remediation in Older Adults With Remitted Depression or Mild Cognitive Impairment.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·2026

Search research articles

Related Experiment Video

Updated: Jun 11, 2026

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation

Published on: August 26, 2011

Emotional processing deficits in late-life depression.

Linda Mah¹, Bruce G Pollock

¹Department of Psychiatry, University of Toronto, Toronto, Canada. lmah@klaru-baycrest.on.ca

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry

|July 2, 2010

Summary

Late-life depression (LLD) involves altered emotional processing, with patients showing different response times to emotional faces compared to healthy individuals. This suggests unique neurobiological underpinnings in LLD distinct from younger depression.

More Related Videos

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Related Experiment Videos

Last Updated: Jun 11, 2026

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation

Published on: August 26, 2011

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Area of Science:

Neuroscience
Psychiatry
Gerontology

Background:

Emotion dysregulation is linked to midlife depression and relapse.
The neurobiology of emotional processing in late-life depression (LLD) remains unclear.

Purpose of the Study:

This pilot study aimed to investigate emotional processing in individuals with LLD.

Main Methods:

Eleven LLD patients and 11 healthy comparison subjects (HCs) participated.
Participants viewed faces with various emotional expressions (happy, sad, fearful, neutral).
Tasks included making nonaffective judgments and labeling facial expressions.

Main Results:

HCs exhibited longer response latencies for emotional vs. neutral faces.
LLD patients showed no difference in response latencies across emotions.
LLDs were less accurate in labeling neutral faces.

Conclusions:

LLD is associated with distinct alterations in emotional processing.
These findings differ from mood-congruent biases seen in younger depressed populations.