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Continuous monitoring of urea in blood during dialysis
P Thavarungkul1, H Håkanson, O Holst
1Department of Biotechnology, University of Lund, Sweden.
Biosensors & Bioelectronics
|January 1, 1991
Abstract:
Urease was immobilized to porous glass and used in combination with a conductivity meter for determining urea in standard solutions as well as in blood from a patient undergoing dialysis. The sampling unit involves a possibility for heparinization at the sampling point and a dialysis step prior to exposure to the enzyme column. The unit operates in a linear mode in the concentration range 5-50 mM. Monitoring of dialysis process gave good correlation with off-line analyses.