Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Phase Contrast and Differential Interference Contrast Microscopy

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Correction: Exploration of the effect and mechanism of indirubin on infectious bovine rhinotracheitis virus based on network pharmacology.

BMC veterinary research·2026

Same author

The distinct effects of metabolic syndrome on negative symptoms and on antipsychotic therapy of schizophrenia involve insular volume, functional connectivity, and genetic polymorphisms.

Translational psychiatry·2026

Same author

Experimental and Numerical Investigation of Slenderness Ratio on a Hollow Glued Bamboo Scrimber Column Under Eccentric Compression.

Materials (Basel, Switzerland)·2026

Same author

Liver Transplantation in the Era of Metabolic Bariatric Surgery: A Bibliometric Analysis.

Obesity surgery·2026

Same author

Isolation, Identification, Biological Characteristics, and In Vitro and In Vivo Antibacterial Effects of a Bovine-Derived <i>Escherichia coli</i> Bacteriophage XJA18.

Microorganisms·2026

Same author

Preparation of a multiepitope vaccine candidate for camel bocavirus and evaluation of its immunogenicity in a mouse model.

Frontiers in immunology·2026

Same journal

Fast Prospective Motion Correction for MRI Based on Electromagnetic Induction Coils with Low Footprint and In-place Calibration.

IEEE transactions on bio-medical engineering·2026

Same journal

Digital Twin Modeling of MR Gradient Coils for Accurate Gradient Safety Evaluation of Implantable Medical Devices.

IEEE transactions on bio-medical engineering·2026

Same journal

A Method for Improving Human Joint Moment Estimation during Lower Limb Rehabilitation Training Based on sEMG Signals.

IEEE transactions on bio-medical engineering·2026

Same journal

Assessment of skin stiffness in systemic sclerosis using optical coherence elastography: A comparative study with histology and clinical parameters.

IEEE transactions on bio-medical engineering·2026

Same journal

Modeling Dyadic Interdependence in Endocrine Functioning: A Multilevel Machine Learning Study of Adults with Cancer and Their Caregivers.

IEEE transactions on bio-medical engineering·2026

Same journal

A Kalman Filter-Based Framework for Granger Causality Assessment: Application in Tracking Maternal-Fetal Heart Rate Coupling.

IEEE transactions on bio-medical engineering·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 11, 2026

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization

Published on: September 8, 2023

Correcting optical-axis calculation in polarization-sensitive optical coherence tomography.

Chuanmao Fan¹, Gang Yao

¹Department of Biological Engineering, University of Missouri, Columbia, MO 65211, USA. cf7b6@mail.missouri.edu

IEEE Transactions on Bio-Medical Engineering

|July 3, 2010

Summary

This summary is machine-generated.

Polarization-sensitive optical coherence tomography (PSOCT) misrepresents optical axes due to depth-dependent retardation. A new numerical correction method accurately maps 2-D optical axis distributions in tissues.

More Related Videos

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Related Experiment Videos

Last Updated: Jun 11, 2026

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization

Published on: September 8, 2023

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Area of Science:

Biomedical Optics
Medical Imaging
Tissue Optics

Background:

Polarization-sensitive optical coherence tomography (PSOCT) is valuable for imaging birefringent tissues.
Current PSOCT methods use circularly polarized light and detect orthogonal components.
Existing studies inaccurately represent optical axes as depth-dependent periodic maps.

Purpose of the Study:

To identify the cause of optical axis misrepresentation in PSOCT images.
To develop a numerical method for correcting optical axis calculations.
To validate the correction method in biological tissue samples.

Main Methods:

Analysis of optical retardation accumulation with depth in PSOCT.
Development of a numerical algorithm to correct optical axis calculations.
Experimental validation using enface PSOCT imaging of tendon tissue.

Main Results:

Confirmed that accumulated optical retardation causes periodic misrepresentation of optical axes.
Successfully implemented a simple numerical correction method.
Demonstrated accurate 2-D optical axis mapping in enface PSOCT images of tendon.

Conclusions:

The proposed numerical correction resolves depth-dependent periodic misrepresentation in PSOCT optical axis images.
Accurate 2-D optical axis mapping is now feasible for birefringent tissues.
This advancement enhances the utility of PSOCT for quantitative birefringence imaging.