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Updated: Aug 19, 2026

Visualization of Vascular and Parenchymal Regeneration after 70% Partial Hepatectomy in Normal Mice
Published on: September 13, 2016
[Behavior of vascularization during hepatic regeneration]
A Aznar Aznar1, T Sánchez Cañizares, M L Bentura Remacha
1Departamento de Medicina y Cirugía Experimental, Hospital Militar Gómez Ulla, Madrid.
Abstract:
In this work, out of 185 rats 120 underwent hepatectomy of 70%. Studies carried out by microradiography and Spalteholz transparence method prove that during the first days after hepatectomy the ratio hepatic parenchyma/vascular texture is increased; this fact comes to be maximal four days after, becoming stabilized toward ten days after. Studies done by Ibas I imaging analyzer in hepatic sections of rats which underwent hepatectomy as compared to those which underwent laparatomy only, show that ratio LCV-LCV, as well as areas and area form of hepatic sanguineous vessels are changing, in the first ones, in a rhythmical way including two phases of greater activity. These variations are evolved, in a different way, in the central zone than in the peripherical one of liver. We try to relate these facts to vascular and humoural theories which explain hepatic regeneration.
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