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Updated: Jun 11, 2026
09:14
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
Cognitive and functional outcome after aneurysmal subarachnoid hemorrhage
Timour Al-Khindi1, R Loch Macdonald, Tom A Schweizer
1University of Toronto, Toronto, Ontario, Canada.
Stroke
|July 3, 2010
Summary
Aneurysmal subarachnoid hemorrhage (aSAH) survivors often face long-term cognitive deficits in memory and executive function. These impairments significantly impact daily activities, work, and quality of life, highlighting the need for further research.
Area of Science:
- Neuroscience
- Neurology
- Clinical Psychology
Background:
- Aneurysmal subarachnoid hemorrhage (aSAH) is a critical neurological emergency.
- While acute treatment is established, long-term consequences on cognitive function and daily life remain less understood.
Purpose of the Study:
- To review and synthesize current research on the long-term cognitive and functional outcomes following aSAH.
- To identify key areas of impairment and factors influencing recovery.
Main Methods:
- Systematic review of empirical studies published within the last 10 years.
- Inclusion criteria focused on studies investigating cognitive and functional outcomes in aSAH patients.
Main Results:
- Sixty-one studies confirmed that aSAH survivors frequently exhibit deficits in memory, executive functions, and language.
- These cognitive impairments negatively affect daily functioning, including activities of daily living, return to work, and overall quality of life.
- Co-occurring depression, anxiety, fatigue, and sleep disturbances exacerbate these deficits.
Conclusions:
- Significant knowledge gaps exist regarding the underlying brain changes responsible for long-term cognitive and functional deficits after aSAH.
- Further investigation into diffuse brain damage and secondary complications (e.g., vasospasm, elevated intracranial pressure) is crucial for a comprehensive understanding.
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