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Related Experiment Videos

Lumbar myelography with amipaque.

L Irstam

    Spine
    |March 1, 1978
    PubMed
    Summary

    Amipaque (metrizamide) is a safe contrast medium for lumbar myelography, with rare serious side effects in 650 patients. Minor reactions occurred in 56%, but adhesive arachnoiditis was significantly less common.

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    Area of Science:

    • Radiology
    • Neurology

    Background:

    • Lumbar myelography often causes side effects with water-soluble contrast media.
    • Amipaque (metrizamide) is a modern contrast agent for spinal imaging.

    Purpose of the Study:

    • To evaluate the safety and efficacy of Amipaque in lumbar myelography.
    • To assess the incidence of adverse reactions and complications associated with Amipaque.

    Main Methods:

    • A series of 650 consecutive lumbar myelographies using Amipaque.
    • Monitoring for early side effects, electroencephalogram (eeg) changes, and adhesive arachnoiditis.

    Main Results:

    • No serious adverse effects were observed in 650 patients.
    • Minor adverse reactions occurred in 56% of patients.
    • Transient eeg changes in 14% and significantly lower incidence of adhesive arachnoiditis compared to other contrast media.

    Conclusions:

    • Amipaque is a safe contrast medium for lumbar myelography with a low rate of serious adverse events.
    • It offers excellent visualization of the spinal subarachnoid space.
    • Amipaque is a valuable tool for spinal investigations, with a favorable safety profile regarding adhesive arachnoiditis.

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