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Initial experience of dual-energy lung perfusion CT using a dual-source CT system in children
1Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. hwgoo@amc.seoul.kr
Insights
Dual-source dual-energy (DE) CT is a feasible method for assessing pediatric lung perfusion and pulmonary emboli. This technique offers acceptable radiation doses for children, enabling detailed lung perfusion analysis.
Area of Science:
- Radiology
- Pediatric Imaging
- Cardiopulmonary Imaging
Background:
- Pulmonary embolism and perfusion abnormalities require accurate diagnostic tools in children.
- Dual-source dual-energy (DE) CT offers potential for simultaneous assessment of lung structure and function.
Purpose of the Study:
- To describe the initial experience and technical aspects of performing dual-source DE lung perfusion CT in pediatric patients.
- To evaluate the feasibility and diagnostic utility of this technique for pulmonary embolism and lung perfusion assessment.
Main Methods:
- Detailed protocol for dual-source DE lung perfusion CT in children, including IV injection and CT dose optimization.
- Generation of weighted-average CT images for pulmonary embolism detection and color-coded perfusion maps for regional lung perfusion analysis.
- Qualitative and quantitative analysis of lung perfusion using the generated maps.
Main Results:
- Dual-source DE CT is technically feasible for pediatric lung perfusion assessment.
- Acceptable radiation doses were achieved.
- The technique allows for detailed evaluation of regional lung perfusion and detection of pulmonary emboli.
Conclusions:
- Dual-source DE CT is a viable emerging technique for evaluating pediatric lung perfusion and pulmonary emboli.
- It offers potential advantages over traditional methods like scintigraphy and cardiac MRI.
- Further studies are warranted to fully establish its role in clinical practice.
Abstract:
Initial experience of dual-source dual-energy (DE) lung perfusion CT in children is described. In addition to traditional identification of pulmonary emboli, the assessment of lung perfusion is technically feasible with dual-source DE CT in children with acceptable radiation dose. This article describes how to perform dual-source DE lung perfusion CT in children, including the optimization of intravenous injection method and CT dose parameters. How to produce weighted-average CT images for the assessment of pulmonary emboli and colour-coded perfusion maps for the assessment of regional lung perfusion is also detailed. Lung perfusion status can then be evaluated on perfusion maps by means of either qualitative or quantitative analysis. Potential advantages and disadvantages of this emerging CT technique compared to lung perfusion scintigraphy and cardiac MRI are discussed.
