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Updated: Jun 11, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
High satisfaction rate ten years after bilateral prophylactic mastectomy - a longitudinal study
E Wasteson1, K Sandelin, Y Brandberg
1Division of Psychology, Department of Social Sciences, Mid Sweden University, Campus Östersund, Östersund, Sweden, and Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian university of Science and Technology (NTNU), Trondheim, Norway
Bilateral prophylactic mastectomy (BPM) in high-risk women led to long-term satisfaction and positive cosmetic outcomes. While most experienced no lifestyle changes, some noted impacts on marital relationships, highlighting the need for ongoing support.
Area of Science:
- Oncology
- Preventive Medicine
- Psychology
Background:
- Bilateral prophylactic mastectomy (BPM) is a surgical option for women with elevated hereditary breast and ovarian cancer risks.
- Previous short-term evaluations (1-3 years) assessed women's perceptions of BPM.
- This study investigates the long-term (10-year) physical and psychological effects of BPM.
Purpose of the Study:
- To evaluate the long-term physical and psychological consequences of bilateral prophylactic mastectomy (BPM).
- To assess the satisfaction and perceived risk of breast cancer post-BPM.
- To understand the impact of BPM on family life, lifestyle, and spousal relationships.
Main Methods:
- A qualitative interview study with 13 women who underwent BPM early in the procedure's history.
- Semi-structured interviews focused on long-term experiences with BPM and immediate breast reconstruction.
- Analysis of women's perceptions regarding physical, psychological, and social outcomes.
Main Results:
- Overall satisfaction with the decision to undergo BPM was high.
- Women reported a negligible perceived risk of future breast cancer.
- Cosmetic results were generally positive; however, 8/13 women reported effects on their spousal relationships (5 negative, 3 positive).
Conclusions:
- Long-term follow-up indicates high satisfaction and positive cosmetic outcomes following BPM.
- While most women maintained their lifestyle, relationship dynamics may be affected.
- Continuous counseling and support throughout the decision, treatment, and follow-up process are recommended for women undergoing BPM.
