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Doctor, how long?

V Da Costa Miranda¹, A B De Souza Fede, F D Martins

¹ABC Foundation School of Medicine, Santo Andre, Brazil.

European Journal of Cancer Care

|July 6, 2010

Summary

Terminal cancer patients on sedation survive a median of 27 hours. Increased sedative dose, opioid use, and dyspnea as a reason for sedation were linked to shorter survival times.

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Published on: October 22, 2019

Area of Science:

Palliative Care
Oncology
Clinical Pharmacology

Background:

Terminal sedation is a crucial aspect of palliative care for cancer patients.
Understanding survival time post-sedation initiation is vital for patient and family support.
Factors influencing survival during terminal sedation require further investigation.

Purpose of the Study:

To quantify the average survival time of cancer patients after initiating terminal sedation.
To identify variables that may influence survival duration during terminal sedation.

Main Methods:

Retrospective cohort analysis of terminal cancer patients who died after starting terminal sedation.
Data collected from a public tertiary Brazilian hospital.
Multivariate analysis to identify independent risk factors.

Main Results:

Median survival time was 27 hours.
Increased sedative drug dosage (OR 1.576), use of opioids alone (OR 1.438), and dyspnea as the cause for sedation (OR 1.564) were independent risk factors for shorter survival.
These factors were associated with significantly reduced survival time post-sedation.

Conclusions:

Terminal cancer patients on sedation typically survive approximately one day.
Identified risk factors can help predict shorter sedation periods.
Further prospective studies are recommended to validate these findings due to the retrospective design and common use of opioids.