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Updated: Jun 11, 2026

Harnessing the Power of MicroRNA Cargoes in Small Extracellular Vesicles Released from Fresh-Frozen Human Brain Sections
Published on: November 8, 2024
Microparticles--messengers of biological information
Friedrich Felix Hoyer1, Georg Nickenig, Nikos Werner
1Department of Cardiology, University Hospital Bonn, Bonn, Germany. felix.hoyer@ukb.uni-bonn.de
Abstract:
Endothelial cell apoptosis is a pivotal step in the development of atherosclerotic disease. Regeneration of the damaged endothelium is an attractive therapy option in the prevention and treatment of atherosclerotic disease. Apoptosis is associated with the release of microparticles (MP). Besides their role as marker of cell damage, recent reports have underlined their role as signalling elements in cell-cell communication. In this review, we focus on the emerging role of circulating MP as transmitters of biological information in cardiovascular disease.
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