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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Reactions02:06

Allergic Reactions

Overview
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...

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Updated: Jun 11, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Allergic rhinitis in children.

Paul J Turner1, Andrew S Kemp

  • 1Department of Allergy and Immunology, The Children's Hospital at Westmead, New South Wales, Australia. pault1@chw.edu.au

Journal of Paediatrics and Child Health
|July 6, 2010
PubMed
Summary
This summary is machine-generated.

Allergic rhinitis in children is often undiagnosed. Intranasal steroids are best for persistent symptoms, while antihistamines help with pollen-induced allergic rhinitis.

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Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
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Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Area of Science:

  • Pediatric Allergy and Immunology
  • Otorhinolaryngology
  • Clinical Therapeutics

Background:

  • Allergic rhinitis affects up to 40% of children, frequently remaining undiagnosed.
  • Effective management hinges on accurate symptom assessment for appropriate treatment selection.
  • Allergen avoidance is often challenging in real-world scenarios.

Purpose of the Study:

  • To review current therapeutic options for allergic rhinitis in children.
  • To differentiate the efficacy of antihistamines versus intranasal steroids based on allergen type and symptom presentation.
  • To discuss the role and limitations of immunotherapy in managing allergic rhinitis.

Main Methods:

  • Literature review of studies on allergic rhinitis treatments in pediatric populations.
  • Analysis of symptom profiles and their correlation with specific allergens (e.g., house dust mite, pollen).
  • Comparison of treatment outcomes for antihistamines, intranasal steroids, and immunotherapy.

Main Results:

  • Antihistamines provide limited relief for perennial allergens like house dust mite, particularly for nasal obstruction.
  • Antihistamines are effective for pollen-induced symptoms such as nasal itch, rhinorrhoea, and sneezing.
  • Intranasal steroids are the preferred treatment for persistent moderate-to-severe allergic rhinitis, outperforming antihistamines in relieving nasal obstruction.

Conclusions:

  • Intranasal steroids are the mainstay for persistent allergic rhinitis, with efficacy dependent on proper usage and compliance.
  • Immunotherapy presents a potentially effective but costly option for specific pollen allergies, though its benefit in house dust mite rhinitis is debated.
  • Accurate diagnosis and tailored treatment strategies are crucial for managing pediatric allergic rhinitis effectively.