Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Radiation, diagnosis, and management.

A C Upton1

  • 1Institute of Environmental Medicine, New York University Medical Center, NY 10016.

Cancer Detection and Prevention
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ionizing radiation and aging.

Project report. USAF School of Aviation Medicine·2014
Same author

Late somatic effects of internally deposited radioisotopes.

Project report. USAF School of Aviation Medicine·2014
Same author

Chemical protection of the mouse against leukemia induction by x-rays.

Project report. USAF School of Aviation Medicine·2014
Same author

Comments on the article 'Defining hormesis', by EJ Calabrese and LA Baldwin.

Human & experimental toxicology·2002
Same author

Radiation hormesis: data and interpretations.

Critical reviews in toxicology·2001
Same author

Salud Ocupacional.

International journal of occupational and environmental health·1999
Same journal

Melanoma metastasis to the breast: a diagnostic pitfall.

Cancer detection and prevention·2009
Same journal

Development of a rat model by 3,4-benzopyrene intra-pulmonary injection and evaluation of the effect of green tea drinking on p53 and bcl-2 expression in lung carcinoma.

Cancer detection and prevention·2009
Same journal

Combined effect of NAT2, MTR and MTHFR genotypes and tobacco on bladder cancer susceptibility in Tunisian population.

Cancer detection and prevention·2009
Same journal

Vitamin D receptor gene polymorphism(s) and breast cancer risk in north Indians.

Cancer detection and prevention·2009
Same journal

Epidemiology of primary brain tumors in the Middle Eastern population in California, USA 2001-2005.

Cancer detection and prevention·2009
Same journal

Lifetime consumption of alcoholic beverages and risk of 13 types of cancer in men: results from a case-control study in Montreal.

Cancer detection and prevention·2009
See all related articles

Radiation exposure has two types of effects: nonstochastic effects with thresholds and stochastic effects without thresholds, such as cancer. Current radiation protection limits exposures to prevent nonstochastic effects and minimize stochastic risks.

Area of Science:

  • Medical Physics
  • Radiation Biology
  • Public Health

Background:

  • Ionizing and nonionizing radiations induce diverse biomedical effects.
  • These effects are categorized as nonstochastic (threshold effects) and stochastic (no-threshold effects).
  • Stochastic effects include mutagenic, carcinogenic, and teratogenic outcomes.

Purpose of the Study:

  • To differentiate between nonstochastic and stochastic radiation effects.
  • To outline current radiation risk management strategies.
  • To explain the principles behind dose limitation for radiation protection.

Main Methods:

  • Review of established radiobiological principles.
  • Analysis of current radiation protection guidelines.
  • Categorization of radiation-induced biological responses.

Related Experiment Videos

Main Results:

  • Nonstochastic effects require exceeding a specific radiation dose threshold for occurrence.
  • Stochastic effects, like cancer, are probabilistic and assumed to have no safe threshold.
  • Radiation risk management focuses on preventing nonstochastic effects and limiting stochastic risks.

Conclusions:

  • Effective radiation protection necessitates distinct strategies for nonstochastic and stochastic effects.
  • Dose limits are crucial for managing cumulative radiation exposure and associated risks.
  • Understanding effect thresholds is fundamental to radiation safety protocols.