Leptin in human physiology and therapeutics

Tina A Dardeno1, Sharon H Chou, Hyun-Seuk Moon

  • 1Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, United States.

Summary

Leptin, a key hormone for energy balance, is effective for treating leptin deficiency. However, most obese individuals show leptin resistance, limiting its use in general obesity treatment.

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