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Prevalence of pediatric dyslipidemia: comparison of a population-based claims database to national surveys

Jie Li1, Stephen P Motsko, Earl L Goehring

  • 1Department of Research, The Degge Group, Ltd, Arlington, VA 22209, USA. jli@deggegroup.com

Pharmacoepidemiology and Drug Safety
|July 6, 2010
PubMed

Insights

Pediatric dyslipidemia affects 22.9% of children, consistent with national data. Specific lipid abnormalities vary by age and gender in children with dyslipidemia.

Area of Science:

  • Pediatric Endocrinology
  • Cardiovascular Health
  • Public Health

Background:

  • Pediatric dyslipidemia is a growing concern with long-term cardiovascular implications.
  • Understanding prevalence and patterns is crucial for early intervention.

Purpose of the Study:

  • To determine the prevalence of pediatric dyslipidemia using a large US insurance claims database.
  • To compare this prevalence with data from the National Health and Nutrition Examination Survey (NHANES).

Main Methods:

  • Analysis of laboratory-defined dyslipidemia in children aged 10-18 from the Integrated Healthcare Information Services (IHCIS) database (2003-2006).
  • Comparison with US children's prevalence data from NHANES (1999-2004).

Main Results:

  • 22.9% of children in the IHCIS database had dyslipidemia, similar to the NHANES estimate (23.9%).
  • Elevated triglycerides were most common, followed by elevated total cholesterol.
  • Age and gender influenced specific dyslipidemia types, with older boys showing different patterns than younger boys.

Conclusions:

  • A large claims database confirms the prevalence of pediatric dyslipidemia found in national surveys.
  • Dyslipidemia patterns in children vary by age and sex, necessitating tailored approaches.
Abstract

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