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Updated: Jun 11, 2026

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
Published on: August 16, 2021
High-risk coronary intervention with a percutaneous ventricular assist device in the presence of an unstable left
Navin K Kapur1, Chris Pan, Barath Krishnamurthy
1Tufts Medical Center, Division of Cardiology, 800 Washington Street, Box No. 80, Boston, MA 02111, USA. nkapur@tuftsmedicalcenter.org
Insights
Left ventricular thrombus, a common myocardial infarction complication, was managed with a percutaneous left ventricular assist device (pVAD) during high-risk percutaneous coronary intervention (PCI). This case highlights pVAD utility in complex scenarios involving LV thrombus.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiovascular Devices
Background:
- Left ventricular (LV) thrombus is a frequent complication following myocardial infarction (MI).
- High-risk percutaneous coronary intervention (PCI) often requires mechanical circulatory support.
- Percutaneous left ventricular assist devices (pVADs) and intra-aortic balloon pumps (IABPs) are available support options.
Observation:
- An elderly patient presented with critical double-vessel disease and severely depressed LV function.
- A large, unstable LV thrombus was identified in the context of a mechanical fall causing spinal cord compression.
- The patient required high-risk PCI for their coronary artery disease.
Findings:
- The TandemHeart pVAD was successfully utilized to provide hemodynamic support during high-risk PCI.
- This intervention was performed in the presence of a significant and unstable LV thrombus.
- The use of pVAD facilitated the management of complex coronary anatomy and LV dysfunction.
Implications:
- This case demonstrates the feasibility and potential benefit of using a pVAD in patients with LV thrombus undergoing high-risk PCI.
- pVADs may offer a viable option for hemodynamic stabilization in complex cardiovascular presentations.
- Further research may explore the role of pVADs in mitigating risks associated with PCI in patients with LV thrombus.
Abstract:
Left ventricular (LV) thrombus is one of the most common complications of myocardial infarction (MI). Contemporary devices for mechanical support during high-risk percutaneous coronary intervention (PCI) include intra-aortic balloon pumps (IABPs) or percutaneous left ventricular assist devices (pVADs). We describe the case of an elderly patient presenting with critical double-vessel disease, severely depressed LV function, and a large LV thrombus in the setting of a mechanical fall causing spinal cord compression. In this report, we describe the use of a TandemHeart pVAD during high-risk PCI in the presence of an unstable LV thrombus.
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