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Updated: Jun 11, 2026

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
Published on: January 10, 2019
Optical coherence tomography (OCT) in optic neuritis and multiple sclerosis
C Lamirel1, N J Newman, V Biousse
1Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
Abstract:
Optical coherence tomography (OCT) is a non-invasive imaging technique routinely used in ophthalmology to visualize and quantify the layers of the retina. It also provides information on optic nerve head topography, peripapillary retinal nerve fiber layer thickness, and macular volume, which correlate with axonal loss. These measurements are of particular interest in optic neuropathies and in multiple sclerosis, and OCT parameters are now used as endpoints in neurologic clinical trials.
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