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Ribosome Profiling

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...

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Updated: Jun 11, 2026

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

Published on: December 4, 2015

Applications for profiling the schistosome transcriptome.

Geoffrey N Gobert¹

¹Queensland Institute of Medical Research, Division of Infectious Diseases, Molecular Parasitology Laboratory, 300 Herston Rd, Herston, Brisbane, Queensland 4006, Australia. geoffG@qimr.edu.au

Trends in Parasitology

|July 8, 2010

Summary

This summary is machine-generated.

Gene expression studies using transcriptomics have advanced schistosome parasite research. This review covers parasite-host interactions, environmental impacts, and comparative analyses of parasite populations.

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High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions

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Published on: March 5, 2022

Area of Science:

* Parasitology and Molecular Biology
* Genomics and Transcriptomics

Background:

* Schistosome parasites cause significant global health burdens.
* Gene expression studies have become increasingly vital in understanding these complex organisms.
* Recent advancements in transcriptomics offer powerful tools for schistosome research.

Purpose of the Study:

* To review recent transcriptomics approaches in schistosome research.
* To examine schistosome-host interactions at the molecular level.
* To discuss the utility of transcriptomics in comparing parasite populations.

Main Methods:

* Review of recent transcriptomics studies.
* Analysis of gene expression data from various biological levels (organism, tissue, cellular).
* Examination of studies focusing on host-parasite interactions and environmental influences.

Main Results:

* Transcriptomics has provided significant insights into schistosome biology and host interactions.
* Studies reveal the impact of environmental factors and therapies on parasite gene expression.
* Reciprocal effects of schistosome infection on host gene expression are elucidated.

Conclusions:

* Transcriptomics is a powerful tool for advancing schistosome research.
* Understanding gene expression is crucial for developing effective control strategies.
* Comparative transcriptomics aids in differentiating parasite populations and species.