Related Experiment Video
Updated: Jun 11, 2026
03:10
A Rat Model of Compound Acne
Published on: November 1, 2024
Back and face involvement in hidradenitis suppurativa
Florence Poli1, Pierre Wolkenstein, Jean Revuz
1Departement of Dermatology, Groupe Henri-Mondor, Albert-Chenevier, AP-HP, Paris, France.
Dermatology (Basel, Switzerland)
|July 8, 2010
Summary
Hidradenitis suppurativa (HS) can present with unique facial and back lesions, distinct from acne. These specific HS manifestations require different treatment approaches compared to typical acne.
Area of Science:
- Dermatology
- Clinical Medicine
Background:
- Hidradenitis suppurativa (HS) is often associated with facial and dorsal lesions.
- These lesions are sometimes misdiagnosed as acne.
Purpose of the Study:
- To characterize the distinct skin lesions observed in a cohort of hidradenitis suppurativa patients.
- To differentiate these lesions from acne vulgaris.
Main Methods:
- A cohort of 12 patients with specific skin lesions was selected from a larger group of 648 HS patients.
- Clinical observation and lesion description were the primary methods.
Main Results:
- Patients, predominantly male, exhibited typical HS features along with unique facial/dorsal lesions.
- Distinctive lesions included rope-like scars, plaques with multiple openings, 'worm-eaten scars,' and coalescent nodules.
- All patients had deep round scars; some also presented with pilonidal or epidermal cysts.
- Isotretinoin treatment was ineffective in 7 patients.
Conclusions:
- Certain hidradenitis suppurativa patients present with characteristic facial and back lesions.
- These specific HS lesions are not acne and necessitate distinct therapeutic strategies.
Related Concept Videos
01:27Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
01:21Accessory Structures of the Skin: Sebaceous Glands
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
01:24Healing II: Complications
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
01:29Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
01:20Accessory Structures of the Skin: Sweat Glands
Sweat glands or sudoriferous glands are one of the important accessory structures of the skin. They are small, coiled tubular structures located in the dermis, the middle layer of the skin. Sweat glands are responsible for producing and secreting sweat, a watery fluid that helps regulate body temperature and excrete waste products.
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
01:02Hypodermis
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...