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Related Concept Videos

Ion Exchange01:17

Ion Exchange

Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or basic...

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Related Experiment Video

Updated: Jun 11, 2026

Layer-by-layer Synthesis and Transfer of Freestanding Conjugated Microporous Polymer Nanomembranes
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Published on: December 15, 2015

Ion-Exchange Membranes Prepared Using Layer-by-Layer Polyelectrolyte Deposition.

Guanqing Liu1, David M Dotzauer, Merlin L Bruening

  • 1Department of Chemistry, Michigan State University, East Lansing, Michigan, 48824.

Journal of Membrane Science
|July 8, 2010
PubMed
Summary

Layer-by-layer polyelectrolyte adsorption in porous membranes creates ion-exchange sites with minimal permeability loss. This method effectively binds gold colloids and lysozyme, with capacity enhanced by stacking membranes.

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Last Updated: Jun 11, 2026

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Area of Science:

  • Materials Science
  • Chemical Engineering
  • Nanotechnology

Background:

  • Porous polymeric membranes are crucial in separation processes.
  • Developing efficient ion-exchange membranes is essential for various applications.
  • Modifying membrane surfaces to introduce specific binding sites is an active research area.

Purpose of the Study:

  • To investigate layer-by-layer polyelectrolyte adsorption for creating ion-exchange sites in porous membranes.
  • To evaluate the binding capacity of modified membranes for gold colloids and lysozyme.
  • To explore methods for enhancing membrane binding capacity, such as adjusting ionic strength and stacking.

Main Methods:

  • Utilized layer-by-layer adsorption of polyelectrolytes (poly(styrene sulfonate) and various polycations) onto porous polymeric membranes.
  • Quantified the binding capacity for negatively charged gold colloids and positively charged lysozyme.
  • Investigated the effect of ionic strength during deposition of the terminal layer.
  • Assessed the capacity enhancement through membrane stacking.

Main Results:

  • Polyelectrolyte coating reduced hydraulic permeability by less than 20%.
  • Membranes coated with 3-bilayer poly(styrene sulfonate)/polyethyleneimine (PSS/PEI) films bound 37±6 mg of Au colloids per mL.
  • Binding capacity varied with polyelectrolyte type, with PSS/PEI showing higher capacity.
  • Lysozyme binding capacity increased with ionic strength during the final PSS layer deposition, reaching up to 16 mg/mL.
  • Stacking 3 membranes increased lysozyme binding capacity threefold at 10% breakthrough.

Conclusions:

  • Layer-by-layer polyelectrolyte adsorption is a viable method for creating functional ion-exchange membranes with high binding capacities.
  • The binding capacity can be tuned by selecting appropriate polyelectrolytes and controlling deposition conditions like ionic strength.
  • Membrane stacking offers a simple and effective strategy to significantly enhance the overall binding capacity for target molecules.