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Updated: Jun 11, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Targeting IL-23: insights into the pathogenesis and the treatment of psoriasis

Hermenio Cavalcante Lima1, Alexandra Boer Kimball

  • 1Department of Medical Pathology, Federal University of Parana - Curitiba, PR - Brazil.

Indian Journal of Dermatology
|July 8, 2010
PubMed

Therapeutic experience strongly supports the use of TNF antagonists as important modalities in the treatment of psoriatic arthritis and plaque psoriasis. Studies with anti-IL-12/23 therapeutic agents, which act in different steps of the psoriatic inflammatory cascade, have also shown demonstrable efficacy. Here, we discuss this approach and its potential within the armamentarium for the treatment of psoriasis. Evidences that the selective blocking of IL-23 may be effective and safe therapy are also addressed.

Keywords:
Anti-IL-12/23IL-12IL-17IL-23biological treatmentpsoriasis

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