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Effect of ampicillin and sulbactam/ampicillin on the immune system
M R Gismondo1, G Chisari, A M Lo Bue
1Department of Microbiology, Faculty of Medicine, University of Catania, Italy.
The Journal of International Medical Research
|January 1, 1991
Abstract:
An investigation was carried out into the possible effects of ampicillin and a sulbactam/ampicillin combination on the immune system of healthy subjects. The following immunological variables were compared before and after antibiotic therapy: proliferation response of peripheral mononuclear cells to phytohaemagglutinin; variation of T- and B-lymphocytes; dosage of interleukin-2; and production of immunoglobulin A. The data obtained did not demonstrate any immunodepressive activity by either ampicillin or the sulbactam/ampicillin combination.