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Updated: Jun 11, 2026

A Workflow to Quantitatively Determine Age-Related Macular Degeneration Lesion-Specific Variations in Fundus Autofluorescence
Published on: May 26, 2023
[Impact of cataract and age-related macular denegeration on the results of various perimetry techniques]
Abstract:
The purpose of the investigation is to study the impact of cataract and age-related macular degeneration (AMD) on the results of frequency-doubling technology (FDT) perimetry. Three groups of patients over 40 years of age took part in the clinical trial: 1) patients with cataract only; 2) those with cataract and glaucoma; 3) those with AMD. A control group comprised healthy individuals. Group 1 and 2 patients underwent phacoemulsification (PE) with intraocular lens implantation. Humphrey (HFA) static threshold testing (24-2) (HFA perimetry) and the authors' modified FDT perimetry were used before and 3 to 6 months after surgery. Group 3 patients also underwent microperimetry and optic coherence tomography. Cataract with visual acuity 8/ 20 or worse decreased very similar perception according to the results of FDT perimetry and HFA perimetry. FDT perimetry revealed more scotomas in patients with cataract concurrent with glaucoma. HFA II perimetry was more sensitive in detecting AMD. AMD and visual acuity of 4/20 or worse decreased contrast perception in some central squares of FDT perimetry.
